Daniel J. Ragone, Jr., M.D., PA
Platelet-Rich Plasma Injections
The patient’s platelet concentrate prepared with RegenACR® Kits
Platelets are key factors in hard and soft tissue repair mechanisms and regeneration . They provide essential growth factors,
such as FGF, PDGF, TGF-ß, EGF, VEGF, IGF, which are involved in stem cell migration, differentiation and
proliferation. Additionally,platelets also stimulate fibroblasts and endothelial cells to induce new extracellular matrix deposition and neo-vascularisation respectively to stimulate the body's natural healing process.
Plasma contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes,
growth factors (such as IGF and HGF), and proteins. Among the plasma proteins, the molecules vital for the
coagulation process and for the fibrin polymer formation will serve as a scaffold for cell migration and new tissue regeneration and accelerates the healing of damaged tissues.